ENDOCRINE DRUGS MNEMONICS | MEDICAORISPOTER

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ENDOCRINE DRUGS MNEMONICS

Carbimazole Side Effects :
"LMNOP"
L - Liver dysfunction, Lymphadenopathy
M - Myalgia
N - Neuritis
O - Occasional agranulocytosis (<1 in 200 cases )
P - Psychosis

Corticosteroids Adverse Side Effects:
"CUSHINGS BAD MD"
C - Cataracts
U - Up all night (sleep disturbances)
S - Suppression of HPA axis
H - Hypertension/buffalo Hump
I - Infections
N - Necrosis (avascular)
G - Gain weight
S - Striae
B - Bone loss (osteoporosis)
A - Acne
D - Diabetes
D - Myopathy, moon faces
D - Depression and emotional changes

Diabetes Medication - Oral Hypoglycaemics:
"BAGS"
B - Biguanides :e.g. metformin - reduces insulin resistance, S/E GI upset, lactic acidosis

A - Alpha-glucosidase inhibitors - e.g. acarbose inhibits carbohydrate digestion so reduces intestinal glucose reabsorption, S/E bloating, diarrhoea

G - Glitazones (thiazolidinediones) e.g. pioglitazone, risoglitazone-insulin-sensitising agents causing transcription of Glut-1 receptors, S/E hepatotoxicity

S - Sulphonylureas e.g. gliclazide, tolbutamine-stimulate insulin production from pancreatic beta-cells, S/E weight gain and hypoglycaemia

Glucocorticoids, Adverse effects :
" GLUCOCORTICOIDS"
G - Glaucoma
L - Lunacy (Psychotic episodes)
U - peptic Ulceration
C - Cushing's syndrome
O - Osteoporosis
C - Cataracts (posterior subcapcular in children)
O - Opportunistic infections

Propythiouracil (PTU) Mechanism :
It inhibits "PTU"
P - Peroxidase/Peripheral deiodination
T - Tyrosine iodination
U - Union (coupling)

Rx of Diabetic Ketoacidosis :
"In India (nobody) Support Pakistan Army"
• Insulin
• Intravenous fluids
• Sodium bicarbonate
• Phoshates
• Antibiotics

SIADH Inducing Drugs:
"ABCD"
A - Analgesics: opioids, NSAIDs
B - Barbiturates
C - Cyclophosphamide/Chlorpromazine/Carbamazepine
D - Diuretic (thiazide)

Sex Hormone Drugs ; Male :
" Mr Frank Need Testis "
• Methyltestosterone
• Fluoxymesterone
• Nandrolone
• Testosterone

Steroid Side Effects :
"CUSHINGOID"
C - Cataracts
U - Ulcers
S - Skin: striae, thinning, bruising
H - Hypertension/Hirsutism/Hyperglycemia
I - Infections
N - Necrosis, avascular necrosis of the femoral head
G - Glycosuria
O - Osteoporosis, obesity
I - Immunosuppression
D - Diabetes

Tissues which Do not Need Insulin for Glucose Uptake:
"BRICKLE"
B - Brain
R - RBCs
I - Intestine
C - Cornea
K - Kidney
L - Liver
E - Excercising skeletal muscle

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